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ea0081p736 | Thyroid | ECE2022

Thyroid hormones and platelet activation in COVID-19 patients

Colonnello Elena , Curreli Mariaignazia , Tozzi Rossella , Criniti Anna , Lorusso Emiliano , Gnessi Lucio , Gandini Orietta , Lubrano Carla

Background: The relationships between thyroid hormones (TH) and platelets (PLT) have not been fully established. Physiological concentrations of L-thyroxine (T4) activate human PLT resulting in ATP release and aggregation. On the other hand, subclinical hypothyroidism has been frequently associated with hypercoagulability, in particular mean platelet volume (MPV), a marker of platelet activation, has been found higher in patients with subclinical hypothyroidism. A possible pro...

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ea0081ep358 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Reduction in Oxytocin levels predict body weight loss in patients with obesity after a very low carbohydrate ketogenic diet (VLCKD).

Tozzi Rossella , Basciani Sabrina , Rossetti Rebecca , Balena Angela , Masi Davide , Risi Renata , Veroi Gabriele , Colonnello Elena , Chiara Massari Maria , Curreli Mariaignazia , Gangitano Elena , Watanabe Mikiko , Mariani Stefania , Gnessi Lucio , Lubrabno Carla

Background: Oxytocin (OXT) enhances glucose uptake and lipid utilization in adipose tissue and skeletal muscle.Dysfunction of the OXT system could underlie the pathogenesis of weight gain. Men and women with obesity were reported to have higher OXT blood levels compared to normal weight subjects. In contrast, metabolic syndrome has been associated with reduced fasting serum oxytocin in larger scale mixed gender studies.Aim: Data regarding the oxytocin sy...

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Endocrine Abstracts

Thyroid hormones and platelet activation in COVID-19 patients

Reduction in Oxytocin levels predict body weight loss in patients with obesity after a very low carbohydrate ketogenic diet (VLCKD).

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